Dietary supplement. 1-2 pearls a day before meals. Evening primrose has regulating effects on estrogen, progesterone, prolactin and prostaglandin levels, which makes evening primrose oil a great ally to combat pre-menstrual symptoms (fluid retention, irritability, abdominal pain) GLA is found in a natural in the triglycerides that form vegetable oils, in vegetables and in some nuts; however, one of the best sources is evening primrose seed. The need for a supplementary intake of evening primrose oil increases every day in modern society; where the intake of vegetables, vegetables and unsaturated oils is decreasing. Warnings: in case of epilepsy, consult a doctor.